Katherine E. Strathearn, Ph.D., and Mark E. Rothenberg, Ph.D.
Corning Life Sciences
Kennebunk, Maine 04043
Lentiviruses are enveloped retroviruses that are becoming major biological tools in cell therapy applications. These types of retroviruses are unique for their ability to (a) deliver a stable gene(s) into most non-dividing cells, (b) integrate their genetic cargo into a target chromosome, and (c) increase their versatility by modifying various molecular properties (e.g., modification of glycoproteins around the envelope) (1).